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Benign Prostatic Hyperplasia
We investigate the biological processes that contribute to prostate enlargement and lower urinary tract symptoms, with a focus on patient-relevant mechanisms.
Benign Prostatic Hyperplasia Research
Redefining how we understand benign prostate disease.
We study how inflammation, aging, cellular stress, and tissue remodeling contribute to benign prostatic hyperplasia and lower urinary tract symptoms.
The Popovics Lab combines human prostate tissues, molecular biology, histology, imaging, and translational models to uncover mechanisms that may shape better treatment strategies for benign prostate disease.
BPH & LUTS Mechanisms behind prostate enlargement and urinary dysfunction.
Inflammation Immune and stress pathways that reshape prostate tissue.
Fibrosis Extracellular matrix remodeling and epithelial-stromal crosstalk.
From tissue to mechanism.
Connecting what we see under the microscope to the biological pathways that drive disease.
Translational Science Human tissue. Imaging. Molecular insight.
A modern lab site that feels alive, visual, and research-forward.
Research Focus
Understanding benign prostate disease from multiple angles.
Our work investigates the cellular and molecular changes that contribute to BPH progression, urinary symptoms, and prostate tissue remodeling.
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Inflammation & Cellular Stress
We explore how inflammatory signaling, endoplasmic reticulum stress, and epithelial responses may influence disease-associated changes in the prostate.
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Fibrosis & Tissue Remodeling
We study stromal remodeling, collagen deposition, and epithelial-stromal communication to understand how tissue architecture changes during BPH.
Our Approach
Mechanistic research grounded in real tissue biology.
We use complementary experimental systems to connect molecular pathways with histological and functional changes in prostate disease.
Human prostate tissues Histology, immunostaining, and imaging-based analysis of clinically relevant specimens.
Cellular and molecular tools Modeling epithelial-stromal interactions and stress-related pathways in controlled systems.
Translational models Connecting tissue-level changes with urinary function and disease-relevant outcomes.
People
A curious, collaborative team studying prostate biology.
Our lab brings together trainees, scientists, and collaborators interested in molecular biology, imaging, histology, translational models, and the biology of benign prostate disease.
Meet the full team Training-focused Hands-on research experience across experimental and analytical techniques.
Collaborative Bringing together complementary expertise to ask better biological questions.
Lab Updates
News, publications, and behind-the-scenes science.
Use this section for paper updates, conference photos, new lab members, grant news, outreach, and little glimpses of lab life.
Latest
New website under construction
We are building a new home for Popovics Lab research, resources, and lab updates.
Research
Research highlights coming soon
Featured projects will include BPH, inflammation, fibrosis, imaging, and translational models.
Join Us
Interested in the lab?
Students and collaborators can learn more about our work and how to get in touch.
Interested in our work?
Connect with the Popovics Lab to learn more about our research, collaborations, training opportunities, and ongoing projects.